In the carcinoma of the head of pancreases the structure gives rise to sign and symptoms of pain and pressure.

Common Bile Duct

Hepatic Artery

Inferior Vena

Cava Duodenum

In carcinoma of the head of the pancreas, the common bile duct causes pain and pressure.

Patients with adenocarcinoma of the pancreas typically present with painless jaundice (70%).

Usually due to obstruction of the common bile duct from the pancreatic head tumor.

Weight loss occurs in about 90% of patients.

Abdominal pain occurs in about 75% of patients.