Two brothers, one have blood group A, while one has blood group O. What can be concluded about their parents?
Answer: One parent (at least) must be heterozygous
Explanation
One parent (at least) must be heterozygous.
Blood group genetics:
Blood type is determined by three genes, A, B, and O. A and B are dominant over O, meaning if someone inherits even one A or B gene, they will have blood type A or B, respectively.
If they inherit two O genes, they will have blood type O.
Scenario:
If one brother has blood type A (could be AA or AO genotype) and the other has blood type O (OO genotype), they must have inherited an O gene from each parent.
This means that at least one parent must be heterozygous (AO) for the A gene to produce an A blood type child and an O blood type child.
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